Table 3.
Univariate Cox regression model depicting HR and 95% CI of baseline covariates associated with the risk of developing MACE in patients with CKD (n = 1142)
| HR (95% CI) | P | |
|---|---|---|
| Sex (women) | 0.69 (0.38–1.26) | 0.231 |
| Age (per year) | 1.06 (1.03–1.09) | 0.001 |
| BMI (per kg/m2) | 1.08 (1.03–1.13) | 0.002 |
| Smoking habit (current smoker) | 1.38 (0.64–2.98) | 0.412 |
| Hypertension (yes) | 21.3 (0.4–11 899.5) | 0.342 |
| Dyslipidemia (yes) | 1.47 (0.77–2.83) | 0.241 |
| eGFR (per mL/min/1.73m2) | 0.97 (0.95–0.99) | 0.010 |
| uACR (per mg/g) (n = 670) | 1.00 (1.00–1.00) | 0.065 |
| Total cholesterol (per mg/dL) | 1.00 (0.99–1.01) | 0.663 |
| LDL-C (per mg/dL) | 1.00 (0.99–1.01) | 0.965 |
| HDL-C (per mg/dL) | 0.97 (0.95–0.99) | 0.033 |
| Triglycerides (per mg/dL) | 1.00 (1.00–1.00) | 0.099 |
| Statins (yes) | 1.35 (0.75–2.46) | 0.319 |
| AS (per 1 point) | 1.97 (1.21–3.21) | 0.006 |
| Fasting glucose (per mg/dL) | 1.02 (1.00–1.05) | 0.048 |
| Hb1Ac (per 1%) | 0.47 (0.17–1.25) | 0.129 |
| TyG (per unit) | 1.95 (1.11–3.40) | 0.018 |
| TyG ≥ 8.63 | 2.29 (1.24–4.20) | 0.008 |
Univariate regression Cox analysis for 4-point MACE as a dependent variable. TyG: triglycerides–glucose index; HR: hazard ratio; 95% CI: 95% confidence interval; uACR: urinary albumin–creatinine ratio; TyG = Ln (TG [mg/dL] × glucose [mg/dL]/2).