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. 2022 Jul 7;323(3):F243–F254. doi: 10.1152/ajprenal.00065.2022

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Licensed under Creative Commons Attribution CC-BY 4.0. Published by the American Physiological Society.

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Figure 6. — Effects of heat acclimation (HA) on kidney damage and regeneration after heat stress (HS). A and C: representative periodic acid-Schiff (PAS; A) and proliferating cell nuclear antigen (PCNA; C) stainings of kidney sections (magnification: ×400). PCNA-positive tubules were counted in four randomly selected fields. B: on days 1 and 7, tubular injury scores in the HA + HS group were significantly lower than in the HS group. D: the percentage of PCNA-positive tubules on day 1 was significantly higher in the HA + HS group than in the HS group. Data represent means ± SE from 4 to 6 mice in each group. *P < 0.05; **P < 0.01; ***P < 0.001. Scale bars = 50 μm.