Table 2.
TFV-DP Concentrations (fmol/3 mm punch) by Adherence Groups
| Dosing Phase | No.a | Mean | SD | Median | 25th Quantile | 75th Quantile |
|---|---|---|---|---|---|---|
| Low adherence | 36 | 359 | 202 | 329 | 176 | 555 |
| Moderate adherence | 40 | 616 | 378 | 622 | 332 | 875 |
| Perfect adherence | 36 | 988 | 734 | 914 | 317 | 1530 |
| Week 7 (after the last dose) | ||||||
| Low adherence | 9 | 527 | 134 | 571 | 466 | 610 |
| Moderate adherence | 10 | 995 | 290 | 1038 | 779 | 1168 |
| Perfect adherence | 9 | 1635 | 655 | 1528 | 1375 | 1767 |
| Washout phase | ||||||
| Low adherence | 36 | 373 | 143 | 383 | 276 | 485 |
| Moderate adherence | 40 | 638 | 259 | 585 | 437 | 803 |
| Perfect adherence | 36 | 997 | 562 | 862 | 645 | 1179 |
Abbreviations: TFV-DP, tenofovir-diphosphate; SD, standard deviation.
a
No.: total number of DBS samples.