Figure 14.
Baseline short-circuit current and transepithelial electrical resistivity (TEER) in 2-wk high-fat diet (HFD)-fed CB1 receptor wild-type and knockout (KO) mice. Measurement of baseline Isc in the jejunum (A and C) and ileum (B and D) in male CB1+/+ and CB1−/− mice fed a HFD for 2 wk. Baseline TEER was significantly higher in the jejunum of CB1−/− mice compared with CB1+/+ mice (P = 0.0043). **P < 0.01 compared with WT in Mann–Whitney test. Data are mean ± SE, n = 6/group. WT, wild type.