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. 2022 Aug 22;17(8):e0273041. doi: 10.1371/journal.pone.0273041

Table 1. Mechanical ventilation (univariable analyses).

Demographic and clinical features of a group of post COVID-19 patients associated to invasive.

Variable TotalN (%)a
N = 280
Invasive Mechanical Ventilation
N (%)
P value
Present
N = 168 (60)
Absent
N = 112 (40)
>60 years old 100 (35.7) 56 (33.3) 44 (39.3) 0.309
Male sex 152 (54.3) 101 (60.1) 51 (45.5) 0.016d
Comorbidities
    Hypertension 116 (41.4) 72 (42.9) 44 (39.3) 0.552
    Diabetes 82 (29.3) 49 (29.2) 33 (29.5) 0.957
    Obesity and/or Overweight 227 (81.1) 134 (79.8) 93(83.0) 0.493
    Dyslipidemia 17 (6.1) 10 (6) 7 (6.3) 0.919
    Hypothyroidism 16 (5.7) 5 (3) 11 (9.8) 0.016 d
    Heart disease 7 (2.5) 5 (3) 2 (1.8) 0.532
    History of lung disease 10 (3.6) 1 (0.6) 9 (8) 0.001b,d
    Previously healthy 35 (12.5) 19 (11.3) 16 (14.3) 0.461
Risk factors
    Smoking 110 (39.3) 69 (41.1) 41 (36.3) 0.454
    Biomass exposure 46 (16.4) 23 (13.7) 23 (20.5) 0.130
    Alcoholism 23 (8.2) 17 (10.1) 6 (5.4) 0.155
Clinical presentation
    ≥3 symptoms 184 (65.7) 114 (67.9) 70 (62.5) 0.355
    1–2 symptoms 90 (32.1) 51 (30.4) 39 (34.8) 0.433
    Asymptomatic 6 (2.1) 3 (1.8) 3 (2.7) 0.680
Sequelae
    Respiratory symptoms 182 (65) 103 (61.3) 79 (70.5) 0.103
    Cardiovascular symptoms 52 (18.6) 33 (19.6) 19 (17) 0.572
    General symptoms 152 (54.3) 90 (53.6) 62 (55.4) 0.769
    Musculoskeletal symptoms 94 (33.6) 65 (38.7) 29 (25.9) 0.026 b,d
    Dermatological symptoms 47 (16.8) 34 (20.2) 13 (11.6) 0.058
    Neurological and neuropsychiatric symptoms 175 (62.5) 113 (67.3) 62 (55.4) 0.044 b,d
    Gastrointestinal symptoms 38 (13.6) 27 (16.1) 11 (9.8) 0.135
    Audiologic symptoms 10 (3.6) 7 (4.2) 3 (2.7) 0.511

a Data are presented as N (%).

b Fisher Exact Test was used to report the p value, otherwise Chi squared test was performed.

c COVID-19 = Coronavirus disease 19.

d P values in bold have statistical significance.