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. Author manuscript; available in PMC: 2023 Dec 1.
Published in final edited form as: Eur J Med Chem Rep. 2022 Jun 8;6:100065. doi: 10.1016/j.ejmcr.2022.100065

Table 4.

Inhibition of the post-kainate hippocampal slice electrical burst rate and duration in the rat for MRS-2485.

Reduction of Post-Kainate Hippocampal Slice Electrical Burst Rate and Duration in Rat by MRS-2485

Metric Medial entorhinal cortex hippocampal slices from kainic acid-treated rat
Compound Concentration 100 μM
Number of Slices 5
% Control Burst Rate or Burst Duration 100
% Control Burst Rate 73 ± 9 (SEM)
% Control Burst Duration 53 ± 7 (SEM)