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. 2022 Aug 22;5:123. doi: 10.1038/s41746-022-00664-z

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Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 7 — Center line = median; upper bound of box = 75th percentile; lower bound of box = 25th percentile; and whiskers = minimum to maximum range, with extreme outliers denoted by black dots. P value based on Wilcoxon rank-sum test. B-blocker beta-adrenergic antagonist, CCB calcium channel antagonist.