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. 2022 Aug 22;12:14293. doi: 10.1038/s41598-022-16773-4

Table 3.

CCD experimental design for the SFE of G. procumbens.

Run Factor 1 Factor 2 Factor 3 CCD position
A: Pressure (MPa) B: Temperature (°C) C: Water content in ethanol (%)
1 24 60 30 Factorial
2 24 70 30 Factorial
3 21 58 20 Axial
4 18 70 30 Factorial
5 24 60 10 Factorial
6 21 72 20 Axial
7 25 65 20 Axial
8 21 65 33 Axial
9 21 65 20 Center point
10 18 60 30 Factorial
11 21 65 20 Center point
12 24 70 10 Factorial
13 18 70 10 Factorial
14 18 60 10 Factorial
15 21 65 7 Axial
16 17 65 20 Axial
17 21 65 20 Center point
18 21 65 20 Center point
19 21 65 20 Center point
20 21 65 20 Center point