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. 2022 Aug 22;12:14286. doi: 10.1038/s41598-022-18571-4

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Gene-network interactions between all the genes reported in the regions containing CNVRs in Afghan sheep breeds, produced by Cytoscape functional annotation tool (http://www.cytoscape.org/). Circles of different colors represent (biochemical pathways) and the lines between these circles indicate the interactions between these pathways with each other. Zone 1 include the genes that affecting the skeletal muscle, zone 2 influence the birth weight, fertility, embryonic development and skeletal morphology, zone 3 is containing the genes that effect on skeletal development, cartilage structure, and joint function and zone 4 plays a role in fetal development and development.