Table 1.
Differentially expressed cortical protein spots identified by 2-DE and LC–MS/MS between vehicle- and STZ-treated mice
| Spot No | Gene name | Protein name | MW (kDa) | pI | Accession No | STZ versus vehicle Ratio |
|---|---|---|---|---|---|---|
| 5003 | Protease, serine, 1 | 26.12 | 6.5 | 16,716,569 | 0.27 | |
| 5004 | Unnamed protein product | 11.56 | 6.57 | 12,838,544 | 0.08 | |
| 5005 | CDC42 isoform2 | Cell division cycle 42 isoform 2 | 19.42 | 6.57 | 16,357,472 | 0.17 |
| 5007 | PRDX3 | Peroxiredoxin 3 | 21.74 | 6.64 | 6,680,690 | 0.38 |
| 5012 | FABP5 | Fatty acid binding protein 5 | 10.58 | 6.74 | 6,754,450 | 0.11 |
| 5018 | PFN2 | Profilin 2 | 9.66 | 6.47 | 9,506,971 | 0 |
| 5019 | COX5B | Cytochrome c oxidase subunit 5B | 9.04 | 6.57 | 117,104 | 0 |
| 8003 | NDK1 | Nucleoside-diphosphate kinase 1 | 12.31 | 8.44 | 37,700,232 | 0.64 |
| 8004 | PPIA | Peptidylprolyl isomerase A | 13.08 | 8.46 | 6,679,439 | 0.71 |
| 3315 | UQCR1 |
Ubiquinol-cytochrome-c reductase complex core protein 1 |
49.83 | 5.35 | 14,548,301 | 3.14 |
| 4203 | DDAH1 | Dimethylarginine dimethylaminohydrolase 1 | 39.32 | 5.61 | 14,548,301 | 1.84 |
| 7212 | Sirt2 | NAD-dependent deacetylase sirtuin-2 | 40.09 | 8.23 | 38,258,618 | 2.8 |
| 7618 | CCT6B | T-complex protein 1 subunit zeta-2 | 66.76 | 8.3 | 22,654,292 | 2.87 |
| 8512 | GLUD1 | Glutamate dehydrogenase 1 | 56.98 | 8.88 | 6,680,027 | 8.74 |
| 8607 | STXBP1 | Syntaxin binding protein 1 | 69.98 | 8.53 | 4,507,297 | 3.74 |
| 8613 | HNRNPL | Heterogeneous nuclear ribonucleoprotein L | 69.57 | 8.93 | 46,577,278 | 6.79 |