Table 2.

Mutations detected in CRC samples

Genes	n (Frequency)	Mutation
APC	77%(30/39)	Y935*, Q1291*, R499*, W1049*, E1309*, E1306*, E1306*, Q1429*, E287*, Q1367*, E1309*, L698*, E1169*, R876*, K1370*, G524fs, T1556fs, T935fs, D1318fs, L1488fs, V1099fs, I1401fs, I1401fs, T1332fs, L1382fs, T1556fs, L1489fs, G2227V, G2227V, F1396L
TP53	72%(28/39)	V157F, Y103fs, Y163C, R273H, A161T, Y220C, G108fs, R248Q, M237I, V157R, V157R, R282W, P152L, P152fs, G245S, R281H, G266V, R342*, R248W, R213*, C135F
KRAS	46%(18/39)	G12V, G12D, T58T, G12S, A146T, Q61H, G13D, A59T
PIK3CA	13%(6/39)	E545K, H419P, H1047R, I112F