Fig. 2. The WBC-PLT recovery shape is conserved across multiple types of traumatic, infectious, and ischemic inflammatory stimuli and demonstrates exponential WBC decay and linear PLT growth.

a Six additional types of surgery are associated with a similar average shape of WBC-PLT recovery. b WBC dynamics are well-approximated as simple exponential decay from a maximum WBC, and PLT dynamics as linear growth starting ${\tau }_{\mathrm{PL}{\mathrm{T}}_{\mathrm{delay}}}$ days after the maximum WBC. c Infectious and ischemic inflammatory stimuli demonstrate the same average WBC-PLT recovery shape, and a non-dimensionalized¹⁷ model shows that physiologic responses to all studied inflammatory stimuli share the same characteristic features. d Most patients with good outcomes follow trajectories well-approximated by this model, with median model fits (adjusted R²) of 0.85 and 0.95 for WBCs and PLTs. See Supplementary Fig. 15 for model fits for the other 8 cohorts and Supplementary Fig. 7 for fitted model parameters ($k_{\mathrm{WBC}},k_{\mathrm{PLT}}$), for all cohorts. Source data are provided as a Source data file. WBC: white blood cell count, PLT: platelet count.