TABLE 2.
Renal-protective effects of traditional Chinese herbs.
| Traditional Chinese herb | Animal model | Renal-protective effect | Underlying mechanism | Reference |
|---|---|---|---|---|
| Smilax glabra (Tu-Fu-Ling) | HN rats | sCr, BUN renal pathology | Inhibit renal oxidative stress and inflammation | (Shi et al., 2018; Zhou et al., 2018) |
| Smilax china L. (Ba-Qia, Jin-Gang-Teng) | HN mice | BUN renal pathology | Unclear | Meng et al. (2017) |
| Mesona procumbens Hemsl. (Xian-Cao) | Diabetic rats | No change | Inhibit renal inflammation | Chen et al. (2020) |
| HN mice | ||||
| Scutellariae radix (Huang-Cen) | HN mice | BUN renal pathology | Inhibit renal oxidative stress and fibrosis | Hua et al. (2018) |
| Morus alba L. (Sang-Shu) | HN mice | sCr, BUN | Unclear | (Phimarn et al., 2017; Yuvaraj and Geetha, 2018) |
| Rhododendron oldhamii Maxim. (Zhuan-Hong-Du-Juan) | HN mice | sCr, BUN renal pathology | Unclear | Hunyadi et al. (2013) |
| Chrysanthemum morifolium Ramat. (Ju-Hua) | HN rats | sCr, BUN | Inhibit renal inflammation | Caselli et al. (2016) |
| Liriodendron chinense (Hemsl.) Sarg (E-Zhang-Qiu) | HN mice | sCr, BUN renal pathology | Inhibit renal Inflammation and fibrosis | Sun et al. (2015) |
| Fructus Gardenia (Zhi-Zi) | HN mice | sCr, BUN renal pathology | Inhibit renal inflammation and fibrosis | (Peng et al., 2019; Liu et al., 2020) |
| Poria cocos (Fu-Ling) | HN mice | sCr, BUN renal pathology | Unclear | Liu et al. (2017) |
| Dendrobium officinalis six nostrum (Tie-Pi-Shi-Hu) | HN rats | sCr | Inhibit renal inflammation | Tung et al. (2015) |
HN, hyperuricemic nephropathy; sCr, serum creatinine; BUN, blood urea nitrogen.