TABLE 2.

Table shows class 2 CRISPR-Cas system variants for which CaSilico designs crRNA.

CRISPR-cas system	Cas protein type	Corresponding organism	Application
VI-A	Cas13a/C2c2	Leptotrichia wadei	Nucleic acid detection, vaccination, transcript targeting, and SNP detection
VI-B	Cas13b/C2c6	Prevotella sp. P5-125	Nucleic acid detection, vaccination, transcript targeting, and SNP detection
VI-D	Cas13d	Ruminococcus flavefaciens XPD3002	Nucleic acid detection, vaccination, transcript targeting, and SNP detection
V-A	Cas12a/Cpf1	Lachnospiraceae bacterium ND2006	Nucleic acid detection and genome editing
V-B	Cas12b/C2c1	Alicyclobacillus acidiphilus	Nucleic acid detection and genome editing
V-F1	Cas14a/Cas12f1	Uncultured archaea	SNP detection