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. 2022 Aug 23;96(11):2829–2863. doi: 10.1007/s00204-022-03354-7

Table 9.

Summary of exposure routes, duration of exposure and concentrations of pure cyanotoxins applied in papers examining effects on the cardiovascular system

Cyanotoxin Exposure route Number of studies
Acute Chronic Total
MCs Intraperitoneal 3 5* 8
Oral 3** 3
Intravenous 2 2
Immersion 13 4*** 17
Cellular, in vitro 9 9
NOD Immersion 3 3
CYN Intraperitoneal 2 2
Oral 5 5
Immersion 3 3
Cellular, in vitro 3 3
ATX Intravenous 3 3
Intracerebroventricular 1 1
Immersion 1 1
GNTX Intravenous 1 1
STX Intraperitoneal 2 2
Immersion 2 2
Cellular, in vitro 1 1
LTX Cellular, in vitro 1 1
Total 55 12 67

*7 days–8 months, **7 days –6 months, ***21–60 days