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. 2022 Aug 9;12:963928. doi: 10.3389/fonc.2022.963928

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Copyright © 2022 Huo, Shen, Zhang and Shen

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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BI 2536 inhibits ovarian cancer cells growth in vitro (A) Half-maximal inhibitory concentration curves of BI 2536 evaluated by CCK-8 assay. (B) Colony formation assay of A2780 treated with the indicated concentration of BI 2536. (C, D) Flow cytometry analysis of the proportion of different cell cycle phases in treated A2780 cells. (E) Representative images showing fluorescence staining of BI 2536-treated cells using EdU proliferation assay. **P < 0.01, and ***P < 0.001.