FIGURE 8.

Exploration of the attractors landscape uncovers the regulators that are sufficient for SAM phase transitions. By controlling the decay rates of the FT-GRN components, the attractors landscape is reshaped, and the states of the system can be driven to a contrasting phenotype. The FT-GRN components specified are those which drive changes when they decay faster in a continuous model, this effect is like a conditional gene silencing construct or protein inactivation inducing a phenotype transition. Continuous lines represent model predictions that agree with developmental observations, and discontinuous lines are predictions that have been documented under specific experimental conditions such as gene silencing. Black circles correspond to the initial meristem stage, and the white circles correspond to the final stage after the node was shut down.