TABLE 1.

Potential active compounds of CASR in the treatment of CHD and their ADME parameters.

No.	RT (min)	Compound	OB (%)	DL	Caco-2	MOL ID
P2	3.71	Gweicurculactone	42.92	0.14	1.37	MOL000903
P3	4.11	Zedoalactone A	111.43	0.19	-0.01	MOL004305
P4*	4.15	Zedoarolide B	135.56	0.21	-0.42	MOL004313
P6	4.25	Zedoalactone C	72.82	0.17	-0.21	MOL004307
P7	4.32	Curcumenone	34.17	0.11	0.91	MOL000898
P8	4.39	Wenjine	47.93	0.27	0.30	MOL000906
P9	4.74	(1R,10R)-Epoxy-(-)-1,10-dihydrocurdione	36.73	0.12	0.68	MOL000891
P10	4.78	Curzerenone	57.05	0.11	1.28	MOL000900
P11	4.82	Isoprocurcumenol	46.11	0.10	0.60	MOL000949
P12	4.90	Zedoalactone B	103.59	0.22	-0.08	MOL004306
P14	5.43	Aerugidiol	38.70	0.12	0.10	MOL000897
P16	7.45	Procurcumenol	34.40	0.10	0.67	MOL000961
P17	8.23	(4S)-Dihydrocurcumenone	64.35	0.11	0.76	MOL004327
P18	8.95	Neocurcumenol	87.75	0.13	1.11	MOL004286
P19	9.66	4-epi-Curcumenol	89.38	0.13	1.06	MOL004326
P20*	11.27	Furanodiene	45.11	0.10	1.77	MOL000899
P21	11.27	(+)-Curcumenol	87.82	0.13	1.14	MOL000901
P22*	11.51	Demethoxycurcumin	4.37	0.33	0.31	MOL000946
P23*	12.02	Curcumin	4.37	0.41	0.35	MOL000892
P24*	12.86	Neocurdione	36.65	0.08	0.88	MOL004287
P25*	13.72	β-Elemenone	28.12	0.07	3.79	MOL004337
P26*	13.72	Curdione	7.00	0.08	0.81	MOL000896
P27*	13.73	(+)-Limonene	39.84	0.02	1.83	MOL000023
P28*	15.30	Curzerene	47.86	0.09	1.74	MOL004258
P29	16.01	Furanodienon	44.67	0.11	1.18	MOL001172
P30	16.41	Curcumol	103.55	0.13	1.12	MOL000902
P31	17.38	Isocurcumenol	97.67	0.13	1.11	MOL000889
P33*	18.74	Germacrone	32.50	0.07	1.33	MOL000910
P34*	19.48	β-Elemene	25.63	0.06	1.84	MOL000908

“^*” active compounds from literatures.