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. 2022 Jul 2;21(8):100264. doi: 10.1016/j.mcpro.2022.100264

Table 5.

List of all peptides that matched to an NTR entry and for which a strong homology match to a UniProt entry was found

Accession Match UniProt entry Enzyme Extra info
ENST00000439303_10_10174230_ntr_100db1
Elongin C pseudogene 3, processed pseudogene
1 MDGEEKTCGGCEGPDAMYVKLISSDGHEFIVKR 33 Q15369
Elongin-C
Trypsin 1 AA difference
Possible SNP? Yes
 MDGEEKT GGCEGPDAMYVKLISSDGHEFIVKR
1 MDGEEKTYGGCEGPDAMYVKLISSDGHEFIVKR 33
ENST00000486575_22_20127011_ntr_100db1
RAN binding protein 1, Retained intron
1 MKEETKEDAEEKQ 13 P43487
Ran-specific GTPase-activating protein (RANBP1)
Trypsin, chymotrypsin 1 AA difference
Possible SNP? No
 KEETKEDAEEKQ
189 VKEETKEDAEEKQ 201
ENST00000458332_17_19446852_ntr_111db1
Ribosomal protein S2 pseudogene 46, processed pseudogene
2 ADDAGAAGGPGGPGGPEMGNRGGFRGGF 29 P15880
40S ribosomal protein S2
GluC 1 AA difference
Possible SNP? Yes
 ADDAGAAGGPGGPGGP MGNRGGFRGGF
2 ADDAGAAGGPGGPGGPGMGNRGGFRGGF 29
ENST00000556323_14_92026617_ntr_100db1
Prothymosin alpha pseudogene, processed pseudogene
2 EKKEVVEEAENGRDAPAD 19 P06454 Prothymosin alpha Trypsin, chymotrypsin 1 AA difference
Possible SNP? Yes
 EKKEVVEEAENGRDAPA+
19 EKKEVVEEAENGRDAPAN 36
ENST00000556323_14_92026566_ntr_100db1
Prothymosin alpha pseudogene, processed pseudogene
2 SDAAVDTSSEITTKDLKEKKEVVEEAENGRDAPAD 36 P06454 Prothymosin alpha Trypsin, chymotrypsin 1 AA difference
Possible SNP? Yes
 SDAAVDTSSEITTKDLKEKKEVVEEAENGRDAPA+
2 SDAAVDTSSEITTKDLKEKKEVVEEAENGRDAPAN 36
ENST00000582213_17_7572835_ntr_100db1
Eukaryotic translation initiation factor 4A1, retained intron
9 FPSNWNEIVDSFDDMNLSESLLR 31 P60842 Eukaryotic initiation factor 4A-I Trypsin 2 AA difference
Possible SNP? No
 SNWNEIVDSFDDMNLSESLLR
23 IESNWNEIVDSFDDMNLSESLLR 45
ENST00000403258_6_88276364_ntr_101db1
ACTB pseudogene 8, processed pseudogene
Match to Q6S8J3 Q6S8J3 POTE ankyrin domain family member E and several Actin variants (P68032, P62736, P68133, …) GluC 1 AA difference
Possible SNP? No
12 MASAASSSSLE 22
 MA AASSSSLE
927 MATAASSSSLE 937
Match to P68032 (and other actin variants)
12 MASAASSSSLE 22
 MA AASSSSLE
229 MATAASSSSLE 239
ENST00000402643_6_166064725_ntr_111db1
Glyceraldehyde-3-phosphate dehydrogenase pseudogene 72, Transcribed processed pseudogene
2 ASTGTAKAVGKVIPELNGKL 37 P04406 Glyceraldehyde-3-phosphate dehydrogenase Trypsin 1 AA difference
Possible SNP? Yes
 ASTG AKAVGKVIPELNGKL
209 ASTGAAKAVGKVIPELNGKL 228
ENST00000530835_11_90283408_ntr_011db2
Tubulin alpha pseudogene 2, processed pseudogene
70 GDVVPKDANAAIATIKTKR 88 Q71U36
Tubulin alpha-1A chain and other tubulin alpha chains: P68363 P0DPH7, Q6PEY2, Q9BQE3
Trypsin 1 AA difference
Possible SNP? Yes
 GDVVPKD NAAIATIKTKR
321 GDVVPKDVNAAIATIKTKR 339
ENST00000530835_11_90283408_ntr_011db2
Tubulin alpha pseudogene 2, processed pseudogene
74 PKDANAAIATIKTKR 89 Q71U36
Tubulin alpha-1A chain
P68363 Tubulin alpha-1B chain and other tubulin alpha chains: P0DPH7, Q6PEY2, Q9BQE3
Trypsin 1 AA difference
Possible SNP? Yes
 PKD NAAIATIKTKR
325 PKDVNAAIATIKTKR 339

For each peptide, the accessions (containing both the Ensembl accession and transcript information) are provided, the column “match” contains the peptide sequence of the identified peptide matched to the NTR and the corresponding sequence in the UniProt protein it was matched to, with the positions of the peptide within the NTR and UniProt proteins. The UniProt accession to which the NTR peptide is matched to, the enzyme (protease) the peptide was identified with and some extra information are listed.