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. 2021 Nov 4;9:1382. Originally published 2020 Nov 30. [Version 2] doi: 10.12688/f1000research.27165.2

Table 2. Diagnostic and Statistical Manual of Mental Disorders-IV criteria for diagnosis of neuroleptic malignant syndrome.

A Development of muscle rigidity and hyperthermia after exposure to neuroleptic medication.
B Two or more of the following:
1. Diaphoresis
2. Dysphagia
3. Tremor
4. Incontinence
5. Altered mental status
6. Mutism
7. Tachycardia
8. Elevated / labile blood pressure
9. Leukocytosis
10. Elevated Ck
C Symptoms in A and B are not because of a substance, neurological, or general medical condition.
D Symptoms in A and B are not accounted for in mental condition.