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. 2022 Aug 9;13:941251. doi: 10.3389/fneur.2022.941251

Table 2.

Comparison of clinical characteristics and NLR in patients presented with dependence or not at 90 day.

IVT MT
Yes (n = 108) No (n = 468) Statistic value p Yes (n = 187) No (n = 164) Statistic value p
Admission NIHSS, median (IQR) 12 (9–15) 4 (2–8) −12.8 <0.001* 16 (12–23) 12 (10–16) −6.4 <0.001*
Age, median (IQR) 76 (68–83) 67 (58–74) −7.2 <0.001* 71 (61–78) 66 (59–74) −3.1 0.002*
Male, n (%) 62 (57) 317 (67) 4.2 0.04* 125 (66) 124 (75) 3.3 0.07
Hypertension, n (%) 79 (73) 338 (72) 0.04 0.85 134 (71) 113 (68) 0.32 0.57
Diabetes mellitus, n (%) 33 (30) 140 (30) 0.02 0.9 60 (32) 41 (25) 2.1 0.14
Hyperlipidemia, n (%) 5 (4) 42 (9) 2.2 0.14 16 (8) 23 (14) 2.6 0.1
Current smoker, n (%) 36 (33) 109 (23) 4.7 0.03 2 (1) 5 (3) 1.8 0.2
Stroke history, n (%) 11 (10) 27 (6) 2.8 0.09 34 (18) 21 (13) 1.9 0.2
mRS 0–1 before stroke, n (%) 101 (94) 448 (96) 0.9 0.3 169 (90) 141 (86) 1.6 0.2
Atrial fibrillation, n (%) 46 (42) 118 (22) 13.0 <0.001* 92 (49) 64 (39) 3.7 0.06
Admission NLR, median (IQR) 4.1 (2.5–6.1) 2.4 (1.6–4.0) −4.8 <0.001* 4.5 (2.7–6.8) 3.9 (2.4–6.8) −1.5 0.13
Day 1 NLR, median (IQR) 6.2 (4.4–10) 3.1 (2.2–4.9) −8.9 <0.001* 6.4 (4.1–9.3) 5.2 (3.6–7.9) −2.5 0.01*
Day 1 NHISS, median (IQR) 13 (10–20) 3 (1–5) −13.9 <0.001* 12 (7–22) 7 (3–10) −14.1 <0.001*
Stroke onset to treat time, min, median (IQR) 166 (127–188) 163 (122–185) −1.2 0.16 314 (277–353) 321 (271–358) −1.3 0.18
Stroke etiology (TOAST), n (%)
Large-artery atherosclerosis 63 (58) 310 (66) 2.4 0.1 98 (52) 86 (52) 0 0.99
Cardioembolism 16 (15) 112 (24) 4.2 0.04* 80 (43) 76 (46) 0.5 0.5
Other 29 (27) 48 (10) 20.1 <0.001* 9 (5) 2 (2) 3.7 0.05
Anterior circulation, n (%) 93 (86) 404 (86) 0.3 0.6 157 (84) 140 (85) 0.1 0.7

IVT, intravenous thrombolysis; MT, mechanical thrombectomy; NIHSS, National Institutes of Health Stroke Scale; IQR, interquartile range; NLR, neutrophil over lymphocytes ratio.

*

Statistically significant.