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. 2022 Aug 9;13:941251. doi: 10.3389/fneur.2022.941251

Table 3.

Comparison of clinical characteristics and NLR in patients presented with sICH or not.

IVT MT
Yes (n = 43) No (n = 533) Statistic value p Yes (n = 39) No (n = 312) Statistic value p
Admission NIHSS, median (IQR) 13 (8–17) 5 (2–10) −6.5 <0.001* 16 (11–22) 14 (11–19) −1.51 0.13
Age, median (IQR) 75 (67–83) 68 (58–76) −3.4 0.001* 70 (59–78) 69 (60–76) −0.39 0.69
Male, n (%) 22 (51) 361 (68) 4.9 0.03* 28 (72) 203 (74) 0.69 0.4
Hypertension, n (%) 31 (72) 376 (71) 0.05 0.83 29 (74) 218 (70) 0.34 0.56
Diabetes mellitus, n (%) 16 (37) 157 (29) 1.14 0.3 17 (44) 84 (27) 4.6 0.03*
Hyperlipidemia, n (%) 1 (2) 46 (9) 2.1 0.15 8 (21) 31 (10) 3.9 0.05
Current smoker, n (%) 9 (20) 136 (26) 0.4 0.5 1 (3) 6 (2) 0 1
Stroke history, n (%) 2 (5) 36 (7) 0.3 0.6 6 (15) 49 (16) 0.003 0.96
mRS 0–1 before stroke, n (%) 33 (77) 507 (95) 22.9 <0.001* 35 (91) 275 (88) 0.001 0.98
Atrial fibrillation, n (%) 21 (49) 143 (27) 9.6 0.002* 20 (51) 136 (44) 0.83 0.36
Admission NLR, median (IQR) 4.2 (2.2–5.9) 2.5 (1.6–4.2) −3.2 0.001* 3.6 (2.2–6.0) 4.3 (2.5–6.8) −0.97 0.33
Day 1 NLR, median (IQR) 7.1 (3.9–10.6) 3.3 (2.3–5.3) −5.3 <0.001* 6.1 (4.1–9.4) 5.8 (3.8–8.6) −0.73 0.47
Day 1 NHISS, median (IQR) 16 (9–26) 3 (1–7) −8.1 <0.001* 21 (12–29) 11 (6–18) −4.1 <0.001*
Stroke onset to treat time, min, median (IQR) 164 (122–182) 167 (123–185) −1.1 0.2 315 (277–352) 318 (270–356) −1.3 0.2
Stroke etiology (TOAST), n (%)
Large-artery atherosclerosis 29 (67) 343 (64) 1.1 0.3 20 (51) 164 (53) 0.02 0.9
Cardioembolism 11 (26) 117 (22) 0.3 0.6 17 (43) 139 (45) 0.01 0.9
Other 4 (9) 73 (14) 0.07 0.4 2 (5) 9 (3) 0.07 0.8
Anterior circulation, n (%) 35 (82) 462 (87) 0.94 0.3 38 (97) 259 (83) 5.5 0.01

IVT, intravenous thrombolysis; MT, mechanical thrombectomy; NIHSS, National Institutes of Health Stroke Scale; IQR, interquartile range; NLR, neutrophil over lymphocytes ratio.

*

Statistically significant.