IHC staining and quantification of serial sections of biopsies from ON101- or placebo-treated wounds. (a–e) Images of IHC results for (a) anti‒Ly-6C/6G, (b) anti-CD3, (c) anti-MOMA2, (d) anti-MMP9, and (e) anti-K14 within wound biopsies of db/db mice at the indicated time points. Quantified results for each antibody are shown on the right (except for anti-K14) and are expressed as means ± SEMs (n = 8 per group). Bar = 250 μm. D, day; IHC, immunohistochemistry; K14, keratin 14; MMP9, matrix metalloproteinase 9.