Table 1. Baseline characteristics of the patients with MAFLD.
| NHANES cohort (n=2,622) | Asian cohort (n=293) | P-value | |
|---|---|---|---|
| Age (years) | 50.70±18.36 | 49.47±13.49 | 0.264 |
| Male, n (%) | 1,388 (52.94) | 157 (53.58) | 0.833 |
| BMI (kg/m2) | 32.47±6.83 | 29.64±6.89 | <0.001 |
| Diabetes mellitus, n (%) | 706 (26.93) | 161 (54.95) | <0.001 |
| Hypertension, n (%) | 1,304 (49.73) | 132 (45.05) | 0.190 |
| Platelet (×109/L) | 248.62±65.91 | 245.33±83.78 | 0.433 |
| Albumin (g/dL) | 4.10 (3.80, 4.30) | 4.16 (3.80, 4.40) | 0.001 |
| ALT (U/L) | 20.0 (15.0, 30.0) | 74.0 (40.0, 111.0) | <0.001 |
| AST (U/L) | 20.0 (16.0, 25.0) | 52.0 (33.5, 75.5) | <0.001 |
| TBIL (µmol/L) | 6.8 (5.1, 8.6) | 13.6 (10.0, 19.0) | <0.001 |
| GGT (U/L) | 24.0 (17.0, 37.0) | 82.0 (43.5, 137.5) | <0.001 |
| Triglyceride (mmol/L) | 1.45 (1.01, 2.12) | 1.67 (1.23, 2.42) | 0.247 |
| HDL-C (mmol/L) | 1.22 (1.03, 1.42) | 1.51 (1.12, 2.00) | 0.025 |
| Glycohemoglobin (%) | 6.03±1.21 | 7.68±1.65 | <0.001 |
| hs-CRP (mg/L) | 2.52 (1.20, 5.28) | 2.36 (0.82, 6.13) | 0.913 |
| HOMA-IR | 3.79 (2.43, 6.38) | 4.54 (2.78, 6.20) | 0.825 |
ALT, alanine aminotransferase; AST, aspartate aminotransferase; BMI, body mass index; hs-CRP, high-sensitivity C-reactive protein; GGT, γ-glutamyl transpeptidase; HDL-C, high-density lipoprotein cholesterol; HOMA-IR, homeostasis model assessment of insulin resistance; TBIL, total bilirubin.