Table 3. Comparison of the performance among NFS, APRI, FIB-4, and BARD in the Asian cohort.

	Cutoffs	AUROC	Accuracy (%)	Sensitivity (%)	Specificity (%)	PPV (%)	NPV (%)	PLR	NLR	DOR	Youden’s index
NFS	−1.455		61.7	67.4	59.4	40.8	81.5	1.66	0.55	3.02	0.269
	−0.372	0.699	72.0	53.5	79.7	52.3	80.5	2.64	0.58	4.55	0.332
	0.676		71.2	14.7	94.7	57.7	73.4	3.28	0.87	3.77	0.121
FIB-4	1.21	0.683	62.1	75.6	56.5	41.9	84.8	1.74	0.43	4.05	0.321
	1.30		61.4	67.4	58.9	40.6	81.3	1.64	0.55	2.98	0.264
	1.45		65.9	60.5	68.1	44.1	80.6	1.90	0.58	3.28	0.297
	2.67		70.6	26.7	88.9	50.0	74.5	2.41	0.82	2.94	0.151
	3.25		70.3	18.6	91.8	48.5	73.1	2.27	0.89	2.55	0.116
APRI	0.3	0.625	49.2	90.7	31.9	35.6	89.2	1.33	0.29	4.59	0.226
	0.5		52.9	65.1	47.8	34.1	76.7	1.25	0.73	1.71	0.130
	1.5		69.6	17.4	91.3	45.5	72.7	2.01	0.90	2.23	0.097
BARD	2	0.615	55.2	67.4	50.2	36.0	78.8	1.36	0.65	2.09	0.177

Best cutoff value is presented in italic. AUROC, area under the receiver operating characteristic curve; DOR, diagnostic odds ratio; NLR, negative likelihood ratio; NPV, negative predictive value; PLR, positive likelihood ratio; PPV, positive predictive value.