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. 2022 Aug 9;16:880267. doi: 10.3389/fncel.2022.880267

FIGURE 2.

FIGURE 2

EA treatment markedly improved multiple functional outcomes after WD-TBI. (A) Accelerating rotarod test, (B,C) balance and motor coordination testing (beam walk test), (D,E) adhesive removal test. In all behavioral tests, mice in WD group displayed severe functional deficits compared to the Control group. WD+EA group significantly attenuated those deficits. WD+EA-NAP group had no significant effect on any deficits at any time of testing, except on Day 1 in (D). Data are the means ± S.E.M. of at least three independent experiments. *p < 0.05, **p < 0.01, ***p < 0.001 (statistical testing was performed by one-way ANOVA/Newman-Keuls test). The number underneath each bar in (A–E) refers to the number of mice used in the study group. The detailed data points are presented in Supplementary Figure 3. The F values of one-way ANOVA for (A–E) are presented in Supplementary Table 1.