Table 1.

Data set of 5-benyl-4-thiazolinone derivatives along with their inhibitory activities.

Sr No.	R1	R2	R	IC50 (μM)	pIC50
1	CO2CH2CH3	CH3	2-OH	28.78	4.5409
2	CO2CH2CH3	CH3	3-OH	43.57	4.3608
3	CO2CH2CH3	CH3	3-OCH3	73.11	4.1360
4	CO2CH2CH3	CH3	3-F	64.38	4.1912
5	CO2CH2CH3	CH3	3-Cl	78.72	4.1039
6	CO2CH2CH3	CH3	4-CO2H	36.46	4.4381
7	CO2CH2CH3	CH3	4-CO2Me	94.02	4.0267
∗8	CO2CH2CH3	CH3	4-NHAc	44.11	4.3554
9	CO2CH2CH3	CH3	4-OH	16.33	4.7870
10	CO2CH2CH3	CH3	2-OH-3-OCH3	19.21	4.7164
11	CO2CH2CH3	CH3	3-OCH3-4-OH	13.06	4.8840
12	CO2CH2CH3	CH3	2,4-(OH)2	28.31	4.5480
13	CO2CH2CH3	CH3	3,4-(OH)2	27.11	4.5668
14	CO2CH2CH3	CH3	2-OH-3,5-di NO2	39.86	4.3994
∗15	CO2H	CH3	3-OCH3-4-OH	32.47	4.4885
16	CO2CH3	CH3	3-OCH3-4-OH	30.39	4.5172
17	CO2t-Bu	CH3	3-OCH3-4-OH	27.53	4.5601
18	CO2 CH3	i-Pr	4-OH	19.21	4.7164
∗19	CO2 CH3	i-Pr	2-OH-3-OCH3	28.90	4.5391
20	CO2 CH3	i-Pr	3,4-(OH)2	21.81	4.6613
21	CO2CH3	i-Pr	3-OCH3-4-OH	22.98	4.6386
22	CO2CH3	i-Pr	3,5-(OCH3)2-4-OH	28.67	4.5425
23	CO2CH3	n-Pr	3-OCH3-4-OH	30.43	4.5166
24	H	CH2CO2CH2CH3	3-NO2	46.00	4.3372
25	H	CH2CO2CH2CH3	3-NH2	35.76	4.4466
26	H	CH2CO2CH2CH3	4-CO2H	34.71	4.4595
∗27	H	CH2CO2CH2CH3	4-OH	27.69	4.5576
28	H	CH2CO2CH2CH3	2-OH-3-OCH3	33.90	4.4698
29	H	CH2CO2CH2CH3	3-OH-4-OCH3	28.80	4.5406
∗30	H	CH2CO2CH2CH3	3-OCH3-4-OH	28.04	4.5522
∗31	CH3	CH2CO2CH2CH3	3-OCH3-4-OH	20.30	4.6925
32	Ac	CH3	3-NO2	70.54	4.1515
33	Ac	CH3	3-OH	19.09	4.7191
∗34	Ac	CH3	4-CO2H	31.75	4.4982
35	Ac	CH3	4-OH	20.53	4.6876
36	Ac	CH3	3-OH-4-OCH3	18.28	4.7380
37	Ac	CH3	3-OCH3-4-OH	26.11	4.5831
∗38	Ac	CH3	3,4-OCH2O	42.28	4.3738
∗39	Ac	CH3	3,4-(OH)2	25.30	4.5968
40	NO2	t-Bu	2-CO2H	33.02	4.4812
41	NO2	t-Bu	2-OH	35.36	4.4514
42	NO2	t-Bu	3-NO2	48.24	4.3165
43	NO2	t-Bu	3-OCH3	44.18	4.3547
44	NO2	t-Bu	3-F	32.08	4.4937
45	NO2	t-Bu	4-NHAc	75.78	4.1204
46	NO2	t-Bu	4-OH	38.82	4.4109
∗47	NO2	t-Bu	2-OH-3-OCH3	55.03	4.2594
∗48	NO2	t-Bu	3-OCH3-4-OH	35.21	4.4533

^∗superscript = test set.