Table 9.

Statistical validation results of all possible CoMSIA models.

S/N	Descriptors	Q2	R2	SEE	N
1	Steric (S)	0.501	0.890	0.0655	5
2	Electrostatic (E)	0.489	0.743	0.0955	2
3	Hydrophobic (H)	0.488	0.707	0.1019	2
4	H-Bond Donor(D)	0.439	0.918	0.0568	5
5	H-Bond Acceptor(A)	0.511	0.875	0.0687	4
6	S + E	0.466	0.714	0.1007	2
7	S + H	0.441	0.823	0.0804	3
8	S + D	0.429	0.940	0.0502	7
9	S + A	0.485	0.883	0.0664	4
10	E + H	0.436	0.734	0.0971	2
11	E + D	0.420	0.843	0.0758	3
12	E + A	0.547	0.880	0.0673	4
13	H + D	0.444	0.943	0.0488	7
14	H + A	0.467	0.856	0.0725	3
15	S + E + H	0.438	0.715	0.1005	2
16	S + E + D	0.419	0.946	0.0477	7
17	S + E + A	0.512	0.874	0.0691	4
18	S + H + A	0.454	0.854	0.0732	3
19	S + H + D	0.364	0.745	0.0951	2
20	S + A + D	0.486	0.952	0.0449	7
21	E + A + D	0.526	0.936	0.0502	5
22	E + A + H	0.498	0.847	0.074	3
23	A + H + D	0.491	0.924	0.054	7
24	E + D + H	0.397	0.828	0.079	3
25	S + E + H + D	0.369	0.775	0.0893	2
26	S + E + H + A	0.480	0.871	0.069	4
27	S + H + D + A	0.475	0.925	0.0542	5
28	E + H + D + A	0.534	0.963	0.0395	7
29	S + E + D + A	0.482	0.941	0.0490	6
30	S + E + H + D + A	0.489	0.959	0.0412	7