Figure 5.

Salient feature of actinosomes. Actinosomes are synthetic confinements with a boundary made of polyK and actin filaments. Several properties make them potentially useful containers for synthetic cell research. (a) They are easy to produce without the need for any sophisticated setups. (b) They have a permeable surface allowing small biomolecules to pass through. (c) They can efficiently encapsulate biomolecules owing to the inherent sequestration capacity of condensates. (d) They have the capacity to act as bioreactors to conduct complex reactions like protein translation. (e) The actin-based boundary opens up the possibility of having an interactive membrane for recruiting other proteins, designing signaling cascades, and forming multicellular assemblies.