Fig. 2.

The figure illustrates the hazard of MACE, death, and the cardiorenal composite with a one standard deviation higher 1/eGFR at different levels of ln (100 × ACR) in A and at different levels of ACR in C. It also illustrates the hazard of these outcomes per standard deviation higher ln (100 × ACR) at different levels of 1/eGFR in B, and at different levels of eGFR in D. The figures were based on Cox models that included age, sex, 1/eGFR, ln(100 × ACR), the interaction of these two variables, and squared terms for 1/eGFR and ln (100 × ACR) where appropriate. MACE major adverse cardiovascular events; eGFR estimated glomerular filtration rate; ACR albumin-to-creatinine ratio