Table 1.
Proportion of events and their incidence by fifths of the geometric mean of each person’s kidney disease index
| Overall N = 9115 |
Quintile 1 N = 1823 |
Quintile 2 N = 1823 |
Quintile 3 N = 1823 |
Quintile 4 N = 1823 |
Quintile 5 N = 1823 |
P | |
|---|---|---|---|---|---|---|---|
| Median KDI (10—90) | 0.26 (0.20–0.37) | 0.20 (0.16–0.21) | 0.23 (0.22–0.24) | 0.26 (0.25–0.27) | 0.30 (0.28–0.32) | 0.37 (0.33–0.47) | |
| Median eGFR (10—90) | 74.9 (48.8–106.8) | 97.3 (73.0–126.2) | 85.2 (67.2–109.9) | 76.2 (59.6–98.2) | 67.6 (51.7–86.9) | 51.8 (33.5–69.9) | |
| Median ACR (10—90) | 1.8 (0.3–29.8) | 0.4 (0.1–1.3) | 1.1 (0.4–3.7) | 1.8 (0.6–9.0) | 4.0 (1.0–27.0) | 18.1 (2.2–109.4) | |
| MACE | |||||||
| N (%) | 1161 (12.7) | 149 (8.2) | 175 (9.6) | 194 (10.6) | 264 (14.5) | 379 (20.8) | < 0.001 |
| N/100py | 2.51 | 1.54 | 1.84 | 2.08 | 2.90 | 4.43 | |
| Death | |||||||
| N (%) | 1045 (11.5) | 108 (5.9) | 140 (7.7) | 167 (9.2) | 223 (12.2) | 407 (22.3) | < 0.001 |
| N/100py | 2.19 | 1.09 | 1.43 | 1.74 | 2.36 | 4.56 | |
| Kidney composite | |||||||
| N (%) | 1226 (13.5) | 161 (8.8) | 136 (7.5) | 213 (11.7) | 274 (15.0) | 442 (24.2) | < 0.001 |
| N/100py | 2.71 | 1.68 | 1.43 | 2.31 | 3.08 | 5.55 | |
The kidney composite includes new macroalbuminuria, a sustained decline in eGFR ≥ 40%, or chronic kidney replacement therapy; the P value is from the chi-square test for trend
GM geometric mean; 10–90 the tenth and 90th percentile boundaries; ACR albumin-to-creatinine ratio; eGFR estimated glomerular filtration rate