Table 2.
Treatment | Dose (mg/kg) | Parasitaemia count | ||
---|---|---|---|---|
Day 3 | Day 4 | Day 5 (post inoculation) | ||
Control | – | 9.40 ± 1.23 | 14.40 ± 0.45# | 16.37 ± 1.25# |
BePINH | 2.5 | 3.75 ± 1.08* | 2.92 ± 1.64* | 2.77 ± 1.65* |
10 | 3.70 ± 0.64* | 2.30 ± 2.72* | 2.05 ± 0.72* | |
15 | 2.43 ± 0.86* | 0.83 ± 0.92* | 0.76 ± 1.11* | |
BePBeH | 2.5 | 3.99 ± 0.74* | 2.95 ± 0.49* | 2.93 ± 1.06* |
10 | 3.72 ± 0.64* | 2.50 ± 0.52* | 2.18 ± 0.77* | |
15 | 2.46 ± 0.75* | 0.91 ± 1.62* | 0.79 ± 1.19* | |
ACT | 5 | 0.51 ± 0.26* | 0.26 ± 0.42* | 0.10 ± 0.66* |
Each value represents the mean ± S.E.M, n = 5
ACT artemisinin-based combination therapy
*,#p < 0.05 compared with control and Day 3, respectively (One-way ANOVA; Dunnett’s post hoc)