Table 3.
Treatment | Dose (mg/kg) | Parasitaemia count | |||
---|---|---|---|---|---|
Day 0 | Day 1 | Day 2 | Day 3 | ||
Control | – | 6.76 ± 0.29 | 13.60 ± 0.62# | 14.39 ± 0.27# | 15.02 ± 0.53# |
BePINH | 2.5 | 7.70 ± 2.76 | 7.53 ± 2.49* | 6.61 ± 1.63* | 6.33 ± 2.80* |
10 | 8.26 ± 2.40 | 6.56 ± 2.35* | 5.58 ± 1.79* | 5.04 ± 2.35* | |
15 | 6.63 ± 2.02 | 6.28 ± 1.85* | 5.53 ± 1.63* | 2.93 ± 1.73* | |
BePBeH | 2.5 | 7.83 ± 2.58 | 7.79 ± 2.06 | 7.07 ± 1.65* | 6.64 ± 2.45* |
10 | 6.63 ± 2.10 | 6.77 ± 1.92* | 6.56 ± 2.11* | 5.31 ± 1.01* | |
15 | 6.35 ± 2.02 | 6.69 ± 1.77* | 5.58 ± 1.55* | 2.98 ± 0.57* | |
ACT | 5 | 7.44 ± 2.01 | 6.66 ± 2.05* | 3.03 ± 2.22* | 1.40 ± 1.93*# |
Each value represents the mean ± S.E.M, n = 5
ACT artemisinin-based Combination Therapy
*,#p < 0.05 compared with control and Day 0, respectively (One-way ANOVA; Dunnett’s post hoc)