Table 4.
Treatment | Dose (mg/kg) | Parasitaemia count | |||
---|---|---|---|---|---|
RBC (106/μL) | WBC (103/μL) | PCV (%) | HB (g/dl) | ||
Control | – | 5.16 ± 3.88 | 8.22 ± 1..76 | 19.50 ± 1.59 | 5.75 ± 0.96 |
BePINH | 2.5 | 9.81 ± 1.96 | 9.77 ± 1.37 | 38.25 ± 0.83* | 10.63 ± 0.19* |
10 | 10.63 ± 1.28* | 10.57 ± 2.02 | 36.50 ± 1.10* | 11.03 ± 0.39* | |
15 | 10.86 ± 1.11* | 10.92 ± 1.70 | 37.25 ± 0.96* | 12.18 ± 0.19* | |
BePBeH | 2.5 | 8.24 ± 2.92 | 9.55 ± 1.56 | 36.87 ± 1.21* | 10.71 ± 0.74* |
10 | 9.89 ± 1.31 | 10.41 ± 1.24 | 37.02 ± 0.92* | 10.87 ± 0.81* | |
15 | 10.31 ± 0.29* | 10.85 ± 0.82 | 37.53 ± 1.01* | 11.17 ± 1.25* | |
ACT | 5 | 10.99 ± 1.17* | 10.60 ± 1.70 | 41.50 ± 1.70* | 12.00 ± 0.32* |
Each value represents the mean ± S.E.M, n = 5
ACT Artemisinin-based Combination Therapy, RBC red blood cells, WBC white blood cells, PCV packed cell volume, HB haemoglobin
*p < 0.05 compared with control (One-way ANOVA; Dunnett’s post hoc)