Fig. 1 |. Screening of multiple skin, nares, perianal and oral body sites for prevalence and individual-level bioburden of C. auris colonization.

a, The proportion of residents colonized at each body site. n = 542 independent samples of each of ten body sites of each of 57 residents at the time of the first screening. Data are presented as a point estimate ±95% confidence intervals. An, perianal skin; Ax, axilla; Bu, buccal mucosa; Ea, external auditory canal; Fg, palm and/or fingertips; Ic, inguinal crease; N, anterior nares; Ne, neck; Tc, tracheostomy; To, tongue; Tw, toe web. b, Sensitivity analysis to calculate the proportion of colonized residents captured by screening different groupings of sites. Sensitivity is defined as the proportion colonized at each site grouping divided by the total number of residents identified as colonized at any body site. Dashed vertical lines correspond to the sensitivity of two routine screening strategies targeting the body sites axilla and inguinal crease (left dashed line) and axilla, inguinal crease and nares (right dashed line). A minimum of six sites was required to achieve 100% sensitivity, capturing all colonized individuals. c, Number of viable C. auris, determined by the MPN, plotted for the inguinal crease (n = 16), nares (n = 19) and axilla (n = 16). Groupwise medians are demarcated with black lines. Statistical significance of differences between sites was assessed with the Kruskal–Wallis test (P < 0.05).