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. 2022 Aug 15;9(3):5–23. doi: 10.15586/jkcvhl.v9i3.233

Table 5:

Recent retrospective studies on the oncologic outcomes of stereotactic body radiotherapy to treat localized renal cell carcinoma.

Study Year Experimental design Intervention Patient population Number of patients/studies Outcomes Follow-up Conclusion
Correa et al. 2019 Systematic review, meta-analysis SBRT All stages, RCC Studies = 26
Patients = 372
LC Median = 28 months LC = 97.2%
Siva et al. 2020 Retrospective
Multi-institution
SBRT ≥ T1b, nonmetastatic RCC Patients = 95 CSS
OS
PFS
Median = 2.7 years 4-yr CSS = 91.4%
4-yr OS = 69.2%
4-yr PFS = 64.9%
Yamamoto et al. 2021 Retrospective
Single institution
SBRT Clinical or recurrent T1 RCC Patients = 29 LC
LR
CPF
DSS
OS
Median = 57 months 5-yr LC = 94%
5-yr LRC = 88%
5-yr PFS = 50%
5-yr DSS = 96%
5-yr OS = 68%

CSS, cancer-specific survival; DSS, disease-specific survival; LC, local control; LRC, loco-regional control; OS, overall survival; PFS, progression-free survival; RCC, renal cell carcinoma; SBRT, stereotactive body radiotherapy.