Table 4.

In vivo vessel permeability to fluorescent solutes

Organ	Vessel	Host animal	Method	P (cm s−1) × 10−6 sodium fluorescein	P (cm s−1) × 106 α−lactalbumin	P (cm s−1) × 10−6 albumin	P (cm s−1) × 10−6 70 kDa dextran	Ref.
Brain pial microvessels	Post−capillary venule	Rat	Intravital injection	2.71			0.15	49
Brain cerebral microvessels	Post−capillary venule	Rat	Intravital injection	1.3−1.5			0.11−0.13	51
Brain pial microvessels	Venule	Rat	Intravital injection				0.1	75
Cremaster muscle	Venule	Rat	Intravital injection				0.6	75
Skin		Mouse	In vivo injection			0.163		76
Mesentery	Post−capillary venule	Rat	In vivo cannulation	26	6.9	0.82		52
Mesentery	Post−capillary venule	Rat	In vivo cannulation			0.8−0.9		77
Mesentery	Venular	Frog	In vivo cannulation		1.7			78
Mesentery	Capillary	Frog	In vivo cannulation		2.1−4.0			79
Mesentery	Capillary	Frog	In vivo cannulation	50				80
Coronary	Venule	Pig	Ex vivo cannulation			3.9−6.8		81
Mammary carcinoma in brain		Rat	Intravital injection			0.17		53
LS174T tumor in dorsal skin		Mouse	Intravital injection			0.16		82
Squamous carcinoma		Mouse	Intravital			0.49	0.98	50