Study	Simeone et al. (2017)		Tofighi et al. (2019)
	Study team member	M.D.	A.G.	M.D.	A.G.
Selection bias	Participants representative of target population	Somewhat likely	Somewhat likely	Very likely	Very likely
	Percent of selected individuals who agreed to participate	N/A	N/A	N/A	N/A
	Section rating	Moderate	Moderate	Strong	Strong
Study design	Indicate the study design	Retrospective electronic medical record review	Retrospective electronic medical record review	Survey	Survey
	Study described as randomized	No	No	No	No
	Was randomized method described	N/A	N/A	N/A	N/A
	Was randomized method appropriate	N/A	N/A	N/A	N/A
	Section rating	Weak	Weak	Weak	Weak
Confounders	Important differences between groups pre-intervention	Yes	Yes	No	No
	Indicate % of confounders controlled	Yes	Yes	Can’t tell	Can’t tell
	Section rating	Strong	Strong	Weak	Weak
Blinding	Outcome assessors aware of intervention or exposure status of participants	N/A	N/A	Can’t tell	Can’t tell
	Participants aware of research question	N/A	N/A	Can’t tell	Can’t tell
	Section rating	N/A	N/A	Moderate	Moderate
Data collection	Data collection methods valid	Yes	Yes	Can’t tell	Can’t tell
	Data collection tools reliable	Yes	Yes	Can’t tell	Can’t tell
	Section rating	Strong	Strong	Weak	Weak
Withdrawals and dropouts	Withdrawals and dropouts reported in #s/reasons per groups	N/A	N/A	N/A	N/A
	% of participants completing the study	N/A	N/A	N/A	N/A
	Section rating	N/A	N/A	N/A	N/A
Final score	Discrepancy between reviewers (Y/N)	N	N	N	N
	Reason for discrepancy	N/A	N/A	N/A	N/A
	Final global rating	Moderate	Moderate	Weak	Weak

Note. EPHPP = Effective Public Health Practice Project; SU = substance use.