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. Author manuscript; available in PMC: 2022 Aug 23.
Published in final edited form as: J Autoimmun. 2022 Jul 8;131:102860. doi: 10.1016/j.jaut.2022.102860

Figure 1.

Figure 1.

S. aureus PGN but not B. subtilis PGN induces production of stable IgG anti-dsDNA autoantibodies in C57/B6 mice. C57/B6 mice were treated with PBS (0.2 mL), S. aureus (PGN-SA) or B. subtilis PGN (PGN-BS) (100 μg/mouse/injection), or whole inactivated S. aureus (5×107 CFU/mouse/injection) via i.p. injection twice per week for 8 weeks. Then treatment was stopped for 8 weeks. (A) Serum levels of IgG anti-dsDNA and (B) endpoint serum levels of total IgG in mice at 22 weeks of age. Median ± Interquartile range. *P < 0.05 compared to the PBS group.