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. 2022 Aug 17;7(34):29995–30014. doi: 10.1021/acsomega.2c03007

Figure 1.

Figure 1

Cartoon representation of (a) the SARS-CoV-2 NSP14 structure containing an ExoN domain (blue) and MTase domain (red). (b) Superimposed initial complex structure of NSP14–NSP10 SARS-CoV-2 (PDB ID: 7MC5), SARS-CoV (PDB ID: 5C8U), and MERS-CoV (modeled). (c) Surface representation of the NSP14–NSP10 complex of SARS-CoV-2 (light brown: NSP10, dark brown: NSP14). (d) Surface representation of the NSP14–NSP10 complex of SARS-CoV (cyan: NSP10, navy blue: NSP14). (e) Surface representation of the NSP14–NSP10 complex of MERS-CoV (pink: NSP10, magenta: NSP14).