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. 2021 Oct 18;2:751798. doi: 10.3389/fresc.2021.751798

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Copyright © 2021 Mann, Goh, Holland and Khor.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Phases of cough. Schematic representation of the changes in airflow (liters per second) and subglottic pressure (centimeter of water) during the phases of cough. Phase 1. The glottis opens on activation of the cough reflex, and a deep breath is inhaled (inspiratory phase). Phase 2. The glottis then closes and expiratory muscles forcibly contract (compressive phase), with a transient increase in intrathoracic pressure. Phase 3. The glottis opens with rapid airflow, causing oscillation of the bronchial tissues (expulsive phase).