Table 2:

Adverse Events

Dose cohort	Total patients (n=81)	Number of AEsa (n=6)	Gradeb	Toxicity	Serious adverse event	Relationship to Panitumumab-IRDye800CW
<0.5 mg/kg	12	1 (8.3%)	1	Prolonged QTc	No	Possible
0.5–1.0 mg/kg	35	1 (2.9%)	1	Prolonged QTc	No	Probable
1.0–1.5 mg/kg	12	1 (8.3%)	2	Hypertension	No	Possible
1.5–2.0 mg/kg	12	-	-	-	-	-
2.0–3.0 mg/kg	10	1 (10%)	1	Presyncope	No	Possible
		1 (10%)	1	Prolonged QTc	No	Possible
		1 (10%)	1	Vomiting	No	Possible

^aAE = adverse event

^bGrade 1 = mild, Grade 2 = moderate