Table 1. A list of enhancer-regulated target genes from Late Cluster 1 found to be significantly differentially expressed in the conditional Atoh1 knockout mouse.
The second and third column contain the observed P-value and fold change from the differential expression analysis, respectively. The fourth and fifth columns indicate whether the gene has previously been implicated in cerebellar development and the corresponding reference PubMed ID.
| Gene | p-value (Atoh1-null) | Fold Change (Atoh1-null) | Cerebellar Development | Reference (PMID) |
|---|---|---|---|---|
| Neurod1 | 9.196E-229 | 0.2 | X | 19609565 |
| Nfix | 1.1991E-43 | 0.53 | X | 21800304 |
| Zic1 | 1.3082E-37 | 0.35 | X | 21307096 |
| Barhl1 | 2.2505E-35 | 0.22 | X | 9412507 |
| Zic2 | 2.0968E-20 | 0.34 | X | 11756505 |
| Insm1 | 5.4814E-20 | 0.25 | X | 18231642 |
| Tcf4 | 9.9139E-20 | 0.69 | X | 30830316 |
| Nfia | 1.8675E-16 | 0.6 | X | 17553984 |
| Bhlhe22 | 4.7662E-10 | 0.53 | ||
| Purb | 2.5878E-09 | 0.53 | ||
| Neurod2 | 4.424E-09 | 0.37 | X | 11356028 |
| Klf13 | 1.7938E-06 | 0.72 | ||
| Zfp521 | 3.5899E-06 | 0.8 | X | 24676388 |
| Sox18 | 3.7168E-05 | 0.71 | ||
| Nfib | 0.00021009 | 0.63 | X | 17553984 |