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LIG downregulates the IRE1α/XBP1s pathway by activating SIRT1 in PC12 cells. (a–f) Western blots of BIP, PDI, P-IRE1α, IRE1α, XBP1s, and CHOP. Data represent mean ± SEM (n = 3 per group). ∗P < 0.05, ∗∗P < 0.01, and ∗∗∗P < 0.001 vs. control group; #P < 0.05, ##P < 0.01, and ###P < 0.001 vs. OGD+LIG group.
