Table 2.
Association between the clinical characteristics and gene mutation in the children with acute lymphoblastic leukemia.
| Clinical feature | Group | No. of gene mutation | P value | ||
|---|---|---|---|---|---|
| None | One | Two or more | |||
| Age | <5 years | 15 | 9 | 8 | 0.018∗ |
| 5 years to 10 years | 13 | 10 | 16 | ≤0.001∗∗ | |
| ≥10 years | 3 | 6 | 8 | 0.001∗∗ | |
|
| |||||
| Sex | Male | 16 | 14 | 20 | 0.07 |
| Female | 16 | 11 | 12 | 0.32 | |
|
| |||||
| Risk | Standard | 13 | 3 | 4 | 0.081 |
| Medium | 19 | 18 | 16 | 0.037∗ | |
| High | 0 | 4 | 12 | 0.001∗∗ | |
|
| |||||
| Organ damage | No organ | 22 | 8 | 11 | 0.078 |
| Single organ | 7 | 16 | 19 | 0.063 | |
| Multiple organs | 2 | 1 | 2 | 0.043∗ | |
|
| |||||
| Time taken to enter maintenance∗ | <1 year | 16 | 8 | 7 | 0.096 |
| ≥1 year (s) | 3 | 9 | 8 | 0.016∗ | |
| Recurrence or death | 2 | 2 | 7 | 0.001∗∗ | |
∗ refers to the time taken by the patient to move from the treatment phase (primary treatment) to the maintenance phase (maintenance therapy).