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. 2022 Aug 16;2022:7904293. doi: 10.1155/2022/7904293

Table 2.

Association between the clinical characteristics and gene mutation in the children with acute lymphoblastic leukemia.

Clinical feature Group No. of gene mutation P value
None One Two or more
Age <5 years 15 9 8 0.018∗
5 years to 10 years 13 10 16 ≤0.001∗∗
≥10 years 3 6 8 0.001∗∗

Sex Male 16 14 20 0.07
Female 16 11 12 0.32

Risk Standard 13 3 4 0.081
Medium 19 18 16 0.037∗
High 0 4 12 0.001∗∗

Organ damage No organ 22 8 11 0.078
Single organ 7 16 19 0.063
Multiple organs 2 1 2 0.043∗

Time taken to enter maintenance∗ <1 year 16 8 7 0.096
≥1 year (s) 3 9 8 0.016∗
Recurrence or death 2 2 7 0.001∗∗

∗ refers to the time taken by the patient to move from the treatment phase (primary treatment) to the maintenance phase (maintenance therapy).