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. Author manuscript; available in PMC: 2023 Feb 1.
Published in final edited form as: Oncogene. 2022 Jul 20;41(34):4104–4114. doi: 10.1038/s41388-022-02416-5

Fig. 3. Switch-mediated in vitro cytotoxicity of sCAR-Ts.

Fig. 3.

Using a concentration range of 10 fM to 10 nM of anti-ROR1 Fab-N and Fab-C switches, the cytotoxicity of sCAR-Ts against ROR1-positive K562/ROR1 (A) and JeKo-1 (C) cells, and ROR1-negative K562 (B) and Raji (D) cells was determined at an E:T ratio of 10:1 and measured after 20-h incubation.