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. Author manuscript; available in PMC: 2023 Sep 1.
Published in final edited form as: AJR Am J Roentgenol. 2022 Mar 23;219(3):397–405. doi: 10.2214/AJR.22.27595

Table 2.

Sensitivity and Specificity of Subpleural Nodule Classification

Scheme and Reader Sensitivity p Specificity p
Lung-RADS v1.1 (diameter)
 Reader 1
 Reader 2
93 (77–98) [25/27]
89 (72–96) [24/27]
–
–
31 (25–37) [60/196]
26 (20–33) [51/196]
–
–
Modifieda Lung-RADS v1.1 (diameter)
 Reader 1
 Reader 2
93 (77–98) [25/27]
85 (68–94) [23/27]
>.99b
.32b
151 (44–58) [100/196]
47 (41–54) [93/196]
<.001b
<.001b
Lung-RADS v1.1 (volume)
 Reader 1
 Reader 2
93 (77–98) [25/27]
89 (72–96) [24/27]
>.99b
>.99b
37 (30–44) [72/196]
37 (30–44) [72/196]
.007b
<.001b
Modifieda Lung-RADS v1.1 (volume)
 Reader 1
 Reader 2
93 (77– 98) [25/27]
85 (68–94) [23/27]
>.99c
>.99c
59 (52–66) [116/196]
58 (51–64) [113/196]
.001c
<.001c
NELSON
 Reader 1
 Reader 2
93 (77–98) [25/27]
93 (77–98) [25/27]
>.99b
.32b
12 (8–18) [24/196]
14 (10–19) [27/196]
<.001b
<.001b

Values represent percentage with 95% CI in parentheses and numerator and denominator in brackets. P values obtained with McNemar’s test.

a

Classification of solid intermediate-size nodules with other subpleural location and triangular, polygonal, or ovoid shape as category 2

b

Comparison to Lung-RADS v1.1 (diameter).

c

Comparison to modified Lung-RADS v1.1 (diameter)