Table 3.
Pearson Correlation analysis of alcohol consumption (g/kg) and neurometabolites (mM).
| Alcohol and GABA | Alcohol and Glutamine | Alcohol and Glutamate | |
|---|---|---|---|
| Cingulate Cortex | |||
| Pearson r | 0.7662 | 0.7497 | 0.3919 |
| t | 3.5769 | 3.3987 | 1.2779 |
| p value | 0.0060* | 0.0079* | 0.2332 |
| Nucleus Accumbens | |||
| Pearson r | −0.3599 | −0.2121 | 0.3206 |
| t | 1.1576 | 0.6510 | 1.015 |
| p value | 0.2768 | 0.5313 | 0.3364 |
| Hippocampus | |||
| Pearson r | −0.0495 | −0.0956 | −0.2204 |
| t | 0.1486 | 0.2881 | 0.6780 |
| p value | 0.8852 | 0.7798 | 0.5148 |
Alcohol drinking showed a positive correlation to both GABA (r(9) = 0.7662, p = 0.0060) and Glutamine concentration (r(9) = 0.7497, p = 0.0079) as measured by Magnetic Resonance Spectroscopy (MRS) (n = 6 NVHL, 5 sham).
Values showing statistically significant differences (p < 0.05) between groups are bolded and represented with *.