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. 2022 Aug 11;52:101610. doi: 10.1016/j.eclinm.2022.101610

Table 2.

Association between frailty and the risk of all-cause mortality, nursing home admission, and needing home care. Note: Three models are reported for each outcome, one for each frailty measure: sum of all deficits; sum of deficits, per deficit type; and frailty category. Models for nursing home admission and needing home care accounted the competing risk of death. Reference groups were the following: woman, for sex; non-drinker, for alcohol consumption; non-smoker for smoking status; least deprived, for deprivation index; and fit, for frailty. In (*) both values were < 1, but due to rounding they appear as 0.99, 1. p-values are not reported as all of them were <0.01, except for (**), where p-value = 0.66, and (***), where p-value = 0.86. HR: Hazard Ratio, CI: Confidence Interval, AIC: Akaike’s Information Criterion.

Variable Level Mortality
Nursing home admission
Need for home care
Deficit count
Deficit count, per deficit type
Frailty category
Deficit count
Deficit count, per deficit type
Frailty category
Deficit count
Deficit count, per deficit type
Frailty category
HR 95% CI HR 95% CI HR 95% CI HR 95% CI HR 95% CI HR 95% CI HR 95% CI HR 95% CI HR 95% CI
Deficit count (total) - 1.03 1.03, 1.03 - - - - 1.4 1.40, 1.40 - - - - 1.5 1.50, 1.50 - - - -
Deficit count (diseases) - - - 1.07 1.06, 1.07 - - - - 1.1 1.1, 1.1 - - - - 0.99 0.99, 1 (*) - -
Deficit count (SSLD) - - - 0.93 0.93, 0.94 - - - - 1.9 1.90, 1.90 - - - - 3.4 3.4, 3.4 - -
Frailty Mild - - - - 1.25 1.24, 1.27 - - - - 9.7 9.68, 9.72 - - - - 21 20.98, 21.02
Moderate - - - - 1.44 1.42, 1.46 - - - - 40 39.98, 40.02 - - - - 160 159.98, 160.02
Severe - - - - 1.38 1.36, 1.41 - - - - 87 86.98, 87.02 - - - - 620 619.98, 620.02
Sex Man 1.69 1.68, 1.70 1.7 1.69, 1.71 1.69 1.68, 1.70 0.92 0.91, 0.93 0.89 0.88, 0.90 0.91 0.90, 0.92 1.2 1.19, 1.21 0.97 0.96, 0.98 1.2 1.19, 1.21
Age - 1.1 1.10, 1.10 1.1 1.10, 1.10 1.1 1.10, 1.10 1.1 1.10, 1.10 1.1 1.10, 1.10 1.1 1.10, 1.10 1.1 1.10, 1.10 1 1.10, 1.10 1.1 1.10, 1.10
Deprivation index 2 1.11 1.10, 1.12 1.11 1.10, 1.12 1.11 1.10, 1.12 0.75 0.74, 0.76 0.74 0.73, 0.75 0.74 0.73, 0.75 1.1 1.09, 1.11 1.1 1.09, 1.11 1.1 1.09, 1.11
3 1.19 1.17, 1.20 1.18 1.17, 1.19 1.18 1.17, 1.20 0.75 0.74, 0.76 0.75 0.74. 0.76 0.74 0.73, 0.75 1.2 1.19, 1.21 1.2 1.19, 1.21 1.1 1.09, 1.11
4 1.24 1.22, 1.25 1.23 1.22, 1.25 1.24 1.22, 1.25 0.59 0.58, 0.60 0.6 0.59, 0.61 0.59 0.58, 0.60 1.1 1.09, 1.11 1.2 1.19, 1.21 1.1 1.09, 1.11
5 (More deprived) 1.32 1.30, 1.34 1.31 1.29, 1.34 1.32 1.29, 1.34 0.6 0.58, 0.62 0.6 0.58, 0.62 0.6 0.58, 0.62 1.2 1.19, 1.21 1.2 1.19, 1.21 1.2 1.19, 1.21
Alcohol consumption Low-risk drinker 0.99 0.98, 1 0.98 0.98, 0.99 0.99 0.98, 1 1.1 1.09, 1.11 1.1 1.09, 1.11 1 0.99, 1 0.69 0.68, 0.70 0.78 0.77, 0.79 0.68 0.67, 0.69
High-risk drinker 1.05 1.02, 1.09 1.05 1.01, 1.08 1.05 1.02, 1.09 1.3 1.26, 1.34 1.3 1.26, 1.34 1.3 1.26, 1.33 0.82 0.79, 0.85 0.86 0.83, 0.89 0.81 0.78, 0.84
Smoking status Ex-smoker 1.27 1.26, 1.28 1.27 1.26, 1.28 1.27 1.26, 1.28 0.91 0.90, 0.92 0.91 0.90, 0.92 0.94 0.93, 0.95 0.97 0.96, 0.98 1 0.99, 1 1 0.99, 1.01
Smoker 1.51 1.50, 1.53 1.52 1.50, 1.54 1.52 1.50, 1.53 1.3 1.28, 1.32 1.2 1.18, 1.22 1.3 1.28, 1.32 1 0.99, 1 0.94 0.93, 0.95 1.1 1.09, 1.11
Nursing home admission Yes 2.71 2.68, 2.73 2.86 2.84, 2.89 2.71 2.69, 2.73 - - - - - - - - - - - -
Need for home care Yes 2.44 2.42, 2.46 2.9 2.87, 2.93 2.49 2.47, 2.51 - - - - - - - - - - - -
AIC 8 503 746 8 499 722 8 502 620 8 884 381 8 885 905 8 885 551 9 569 799 9 309 981 9 584 591