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. 2022 Aug 3;8(8):e10050. doi: 10.1016/j.heliyon.2022.e10050

Table 4.

Multivariate COX regression analysis for the prediction of all-cause mortality and cardiovascular mortality.

RC per 5 mg/dL increase
RC ≥ 15.5 mg/dL
NHDL per 5 mg/dL increase
NHDL ≥130 mg/dL
HR (95%CI) P HR (95%CI) p HR (95%CI) P HR (95%CI) p
All-cause mortality
 Model 1 1.06 (1.04, 1.07) <0.001 1.63 (1.43, 1.87) <0.001 0.99 (0.99, 1.00) 0.046 0.84 (0.75, 0.93) 0.001
 Model 2 1.00 (0.98, 1.02) 0.998 0.93 (0.84, 1.07) 0.355 0.99 (0.98, 0.99) <0.001 0.74 (0.67, 0.83) <0.001
 Model 3 0.99 (0.97, 1.01) 0.398 0.94 (0.82, 1.08) 0.400 0.99 (0.98, 1.00) 0.003 0.79 (0.71, 0.89) <0.001

Cardiovascular mortality
 Model 1 1.11 (1.07, 1.15) <0.001 2.33 (1.63, 3.33) <0.001 1.01 (0.99, 1.02) 0.382 0.99 (0.77, 1.26) 0.920
 Model 2 1.07 (1.02, 1.11) 0.003 1.35 (0.94, 1.93) 0.103 1.00 (0.99, 1.02) 0.636 0.93 (0.73, 1.20) 0.589
 Model 3 1.05 (1.01, 1.10) 0.025 1.34 (0.93, 1.94) 0.114 1.01 (1.00, 1.03) 0.073 1.13 (0.87, 1.47) 0.355

Model 1: unadjusted.

Model 2: adjusted for age and sex.

Model 3: adjusted for age, sex, ethnicity, education level, diabetes mellitus, hypertension, smoker, alcohol user, BMI, coronary heart disease, congestive heart failure, stroke, and lipid-lowering drugs.